If aseptic criteria must be met, filling of vials, placement and closure of the bag
needs to take place under a laminar flow/working bench. And all required acces-
sories (vials, stoppers, bag, closing stick etc.) need to be sterile.
But as soon as the bag is closed, you can move your assembly to any freeze-drier
in your facility. Your drug product will be safe - the Lyoprotect@Membrane acts as
a sterile barrier.